Semaglutide for PCOS: A New Hope for Managing Symptoms and Weight
Women's HealthAdvanced TherapiesMedical Weight Loss

Semaglutide for PCOS: A New Hope for Managing Symptoms and Weight

24 Dec 2025
9 min read

Polycystic Ovary Syndrome (PCOS) affects millions of women worldwide, often bringing with it a challenging array of symptoms including irregular periods, hormonal imbalances, acne, unwanted hair growth, and particularly, stubborn weight gain. For women in Los Angeles struggling to manage PCOS, traditional approaches can be frustrating. At Rejuve Clinics in Sherman Oaks, we are now offering Semaglutide as a groundbreaking treatment that addresses many of the core issues associated with PCOS.

Understanding PCOS and Its Challenges

PCOS is a complex hormonal disorder characterized by:

  • Insulin Resistance: A key factor where the body struggles to use insulin effectively, leading to elevated blood sugar and increased insulin levels. This often drives weight gain, especially around the abdomen.
  • Hormonal Imbalance: High levels of androgens (male hormones) contribute to symptoms like acne, excessive hair growth, and hair thinning.
  • Irregular Menstrual Cycles: Ovulation often doesn't occur regularly, leading to irregular periods and fertility challenges.

Managing the weight gain and insulin resistance associated with PCOS has historically been one of the biggest hurdles for patients.

How Semaglutide Helps Women with PCOS

Semaglutide, originally developed for Type 2 Diabetes, has proven to be incredibly effective for weight management, and these benefits extend significantly to women with PCOS. It works primarily as a GLP-1 receptor agonist, mimicking a natural gut hormone that helps regulate appetite and metabolism. For PCOS patients, this translates into several key advantages:

  • Significant Weight Loss: Semaglutide leads to substantial and sustainable weight reduction by reducing appetite and slowing gastric emptying, which is crucial for combating PCOS-related weight gain.
  • Improved Insulin Sensitivity: By improving how the body responds to insulin, Semaglutide can help break the cycle of high insulin levels that often drives many PCOS symptoms.
  • Reduced Androgen Levels: Weight loss and improved insulin sensitivity often lead to a reduction in androgen levels, which can alleviate symptoms like hirsutism (excess hair) and acne.
  • More Regular Menstrual Cycles: For many women, weight loss and better metabolic control can contribute to more consistent and predictable menstrual cycles.

The Rejuve Clinics Personalized Approach

At Rejuve Clinics, we understand that PCOS is highly individual. Our approach begins with a comprehensive functional medicine consultation, including thorough biomarker testing to assess your hormonal profile, insulin sensitivity, and overall metabolic health.

Based on your unique needs, our medical team will develop a personalized treatment plan that may include Semaglutide, potentially combined with:

  • Dietary Guidance: Tailored nutritional plans to support insulin sensitivity and gut health.
  • Lifestyle Coaching: Strategies for exercise and stress management crucial for PCOS.
  • Complementary Therapies: Such as BHRT (Bioidentical Hormone Replacement Therapy) to address specific hormonal imbalances, or IV Therapy for nutrient support.

Conclusion: Take Control of Your PCOS Journey

If you're a woman in Los Angeles struggling with PCOS symptoms and the challenges of weight management, Semaglutide therapy at Rejuve Clinics offers a powerful, medically supervised path forward. We are dedicated to helping you achieve hormonal balance, sustainable weight loss, and an improved quality of life.

Don't let PCOS define your health. Contact Rejuve Clinics in the Sherman Oaks Galleria today to schedule your personalized consultation and explore if Semaglutide is right for your PCOS management.

Frequently Asked Questions

Answers to common questions about this article

While Semaglutide can significantly manage and improve many PCOS symptoms, including weight gain and insulin resistance, it is not considered a "cure." It is a powerful tool for ongoing management and symptom relief.
Avinash Patel

Avinash Patel

Author

Hi, I'm Avinash Patel